Anti-Cytokeratin 5 & 6, Clone EPR1600Y + EPR1602Y

Cytokeratin 5 (58 kD) is expressed in basal, intermediate and superficial cell layers of stratified epithelia as well as transitional epithelia, and in mesothelial cells and mesothelioma. Cytokeratin 6 (56 kD) is also a high molecular weight cytokeratin expressed by proliferating squamous epithelium. Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen's disease. It does not react with pulmonary adenocarcinoma. CK 5/6 is also used as a confirmatory immunostain to recognize lymphoepitheliomas.
Intended Use: IVD