PIK3CA/CEN 3 Dual Color Probe

Catalog Number
FP059-10XE - (10 tests(RTU))Add to cart
FP059-20XE - (20 tests(RTU))Add to cart
eFISH PIK3CA/CEN 3 Dual Color Probe has affinity to PIK3CA gene. The PIK3CA (a.k.a. PI3K-alpha) gene is located on chromosome 3q26.3 and encodes the 110 kDa catalytic subunit of the phosphatidylinositol 3-kinase (PI3K). The use of eFISH PIK3CA/CEN 3 Dual Color Probe along with appropriate filters produces green signal for PIK3CA gene and the hybridization signals of the labeled alpha-satellite-sequences of the centromere of chromosome 3 appear orange. Normal interphase cells or cells without aberrations of chromosome 3, two PIK3CA signals and two chromosome 3 signals appear. Cells with a gene amplification have an increased number of gene specific signals or signal clusters.
Intended Use: IVD