Anti-Anaplastic Lymphoma Kinase (ALK)

Catalog Number
AN874-10M - (100 tests - i6000)Add to cart
AN874-5M - (6 mL (RTU))Add to cart
AY874-50D - (50 tests - Xmatrx Elite)Add to cart
AY874-YCD - (200 tests - Xmatrx Elite)Add to cart
FB-874N - (5 slides - Xmatrx)Add to cart
FG-874N - (5 slides - Manual)Add to cart
NU874-5UC - (0.5 mL (Conc.))Add to cart
NU874-UC - (1 mL(Conc.))Add to cart

Anaplastic lymphoma stained with anti-Human ALKusing DAB chromogen

Anaplastic lymphoma kinase is a receptor tyrosine kinase. Chromosomal translocations involving ALK have been found to be associated with different diseases such as anaplastic large cell lymphomas (ALCLs) and non small-cell lung cancer (NSCLC). The constitutively active fusion proteins are responsible for most of anaplastic large cell nonHodgkin’s lymphomas. The EML4-ALK fusion gene is responsible for approximately 3-5% of NSCLC. EML4-ALK-rearrangement in NSCLC is exclusive and not found in EGFR- or KRAS-mutated tumors.
Intended Use: IVD