Anti-c-Kit / CD117

Catalog Number
AN818-10ME - (100 tests - i6000)Add to cart
AN818-5ME - (6 mL (RTU))Add to cart
NU818-5UCE - (0.5 mL (Conc.))Add to cart
NU818-UCE - (1 mL(Conc.))Add to cart

Stomach stained with anti-Human c-Kit/CD117using DAB chromogen

CD117 is a proto-oncogene, meaning that overexpression or mutations of this protein can lead to cancer. Seminomas, a subtype of testicular germ cell tumors. Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor.
Intended Use: IVD