Anti-Calretinin

Catalog Number
AN747-10M - (100 tests - i6000)Add to cart
AN747-5M - (6 mL (RTU))Add to cart
AY747-50D - (50 tests - Xmatrx Elite)Add to cart
AY747-YCD - (200 tests - Xmatrx Elite)Add to cart
FB-747N - (5 slides - Xmatrx)Add to cart
FG-747N - (5 slides - Manual)Add to cart
NU747-5UC - (0.5 mL (Conc.))Add to cart
NU747-UC - (1 mL(Conc.))Add to cart
Datasheet
SDS

Mesotheloma tissue stained with anti-Calretinin using DAB chromogen

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This antibody recognizes a protein of 31.5kDa, identified as Calretinin. Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. It is abundantly expressed in central and peripheral neural tissues, particularly in the retina and in the neurons of the sensory pathways, and calretinin may play an important role in the survival of nerve cells during disturbances in calcium homeostasis. Calretinin is also expressed by both normal and neoplastic mesothelial cells, and it has been suggested as a useful marker for the identification of malignant mesotheliomas of the epithelial type and for the differentiation of these malignancies of lung adenocarcinoma.
Intended Use: IVD