Anti-Catenin Delta 1 (P120), Polyclonal

Catalog Number
AR706-10R - (100 tests - i6000)Add to cart
AR706-5R - (6 mL (RTU))Add to cart
AW706-50D - (50 tests - Xmatrx Elite)Add to cart
AW706-YCD - (200 tests - Xmatrx Elite)Add to cart
FB-706P - (5 slides - Xmatrx)Add to cart
FG-706P - (5 slides - Manual)Add to cart
PU706-5UP - (0.5 mL (Conc.))Add to cart
PU706-UP - (1 mL(Conc.))Add to cart
Catenins are proteins that are linked to cytoplasmic domain of transmembrane cadherins. P120 Catenin is a memberof this Aemadillo gene family of junctional plaque proteins. The association of catenins to cadherins produces a complex which is linked to the actin filament network. Cytoplasmic accumulation of p120 catenin has been observed in lung cancer, pancreatic cancer, gastric cancer and colon cancers and is associated with poor progress in colon cancer patients. In breast lobular neoplasia, anti p120 Catenin shows a diffuse cytoplasmic immunostaining pattern, while breast ductal neoplasma retains the membrane immunostaining pattern. P120 catenin antibody is useful in differentiation of lobular carcinoma from ductal carcinoma of the breast and in identifying early lesions of lobular neoplasia.
Intended Use: IVD