Anti-c-erbB-2 (HER-2/neu)

Catalog Number
AN753-10M - (100 tests - i6000)Add to cart
AN753-5M - (6 mL (RTU))Add to cart
AY753-50D - (50 tests - Xmatrx Elite)Add to cart
AY753-YCD - (200 tests - Xmatrx Elite)Add to cart
FB-753N - (5 slides - Xmatrx)Add to cart
FG-753N - (5 slides - Manual)Add to cart
NU753-5UC - (0.5 mL (Conc.))Add to cart
NU753-UC - (1 mL(Conc.))Add to cart

Breast cancer stained with anti-Human c-erbB-2 using DAB chromogen

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. Amplification or over-expression of the erbB-2 gene occurs in approximately 15-30% of breast cancers. It is strongly associated with increased disease recurrence and a poor prognosis. Over-expression is also known to occur in ovarian, stomach, and aggressive forms of uterine cancer, such as uterine serous endometrial carcinoma. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarcinomas, as well as transitional cell carcinomas.
Intended Use: RUO