Anti-CD103, Clone EP206

Catalog Number
AN739-10M
(100 tests - i6000)
Qty:
AN739-5M
(6 ml (RTU))
Qty:
AY739-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AY739-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FB-739N
(5 slides - Xmatrx)
Qty:
FG-739N
(5 slides - Manual)
Qty:
NU739-5UC
(0.5 ml (Conc.))
Qty:
NU739-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Colon carcinoma stained with anti-CD103 using DAB chromogen

$0.00
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CD103, also known as integrin alpha E (ITGAE), is an integrin protein that in humans is encoded by the ITGAE gene. It binds integrin beta 7 to form the complete heterodimeric molecular αEβ7 that binds to an extracellular matrix component and cellular counter receptor. They mediate cell adhesion, migration and signaling and are important for T lymphocyte localization. CD103 is expressed on intraepithelial lymphocytes in mucosal areas, including lung and GI tract. In malignancies, CD103 is expressed on more than 95% of intraepithelial CD8+ cells and 40% of mucosa associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-postive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia, the cells express CD103.
Intended Use: RUO