Anti-CD16, Clone 2H7

Catalog Number
AM437-10M - (100 tests - i6000)Add to cart
AM437-5M - (6 mL (RTU))Add to cart
AX437-50D - (50 tests - Xmatrx Elite)Add to cart
AX437-YCD - (200 tests - Xmatrx Elite)Add to cart
FG-437M - (5 slides - Manual)Add to cart
MU437-5UC - (0.5 mL (Conc.))Add to cart
MU437-UC - (1 mL(Conc.))Add to cart

Lymph node stained with Anti-CD16 using AEC chromogen

CD16 antigen is also known as Fc gamma receptor III and has a molecular weight of 50 to 70kD. It is a low affinity Fc receptor for complexed IgG-Fc gamma RIII, expressed on natural killer (NK) cells, granulocytes, activated macrophages and a subset of T cells expressing alpha-beta or gamma-delta T cell antigen receptors. The CD16 antigen exists both as a polypeptide-anchored form (FCgammaRIIIA or CD16A) on NK cells and monocytes/ macrophages and as a glycosylphosphatidyl-inositol (GPI)-anchored form (FcgammaRIIIB or CD16B) on neutrophils. Antibody-dependent cytotoxicity of NK cells is triggered by the engagement of CD16 with the Fc portion of IgG immunoglobulins bound to target cell-associated antigens. This antibody may be useful in the study of NK cell activity in autoimmune, neoplastic and infectious diseases.
Intended Use: IVD