Anti-CD20/MS4A1, Clone IGEL/773

Catalog Number
AM947-10M
(10 mL (RTU))
Qty:
AM947-5M
(6 ml (RTU))
Qty:
AX947-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX947-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
MU947-5UC
(0.5 ml (Conc.))
Qty:
MU947-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Tonsil stained with CD20

$0.00
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The CD20, which is a 33 kDa protein that traverses the cell membrane, initially expresses on pre B-cells and retains on mature B-cells. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is lost upon terminal differentiation into plasma cells. Anti-CD20 can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type.
Intended Use: IVD