Anti-CD3e, Clone C3e/1931

Catalog Number
AM931-10M
(10 mL (RTU))
Qty:
AM931-5M
(6 ml (RTU))
Qty:
AX931-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX931-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
MU931-5UC
(0.5 ml (Conc.))
Qty:
MU931-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Lymph node stained with CD3e

$0.00
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CD3e is part of the T cell receptor-CD3 (TCR-CD3) complex present on T-lymphocyte cell surface that plays an essential role in the adaptive immune response. The CD3-epsilon polypeptide together with CD3-gamma, -delta and –zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers forms the TCR-CD3 complex. The CD3 complex is closely associated with the lymphocyte cell surface with the TCR. CD3e plays an essential role in correct T-cell development. Reportedly, the CD3 complex is involved in signal transduction to the T-cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T-cell surface. The CD3 antigen is a highly specific marker for T cells and is present in the majority of T-cell neoplasms.
Intended Use: RUO