Anti-CD45, Clone 2B11 & PD7/26

Catalog Number
AM941-10M - (10 mL (RTU))Add to cart
AM941-5M - (6 mL (RTU))Add to cart
AX941-50D - (50 tests - Xmatrx Elite)Add to cart
AX941-YCD - (200 tests - Xmatrx Elite)Add to cart
MU941-5UC - (0.5 mL (Conc.))Add to cart
MU941-UC - (1 mL(Conc.))Add to cart

Tonsil stained with CD45

CD45 antigen (leukocyte common antigen), a unique and ubiquitous membrane glycoprotein with a molecular mass of about 200 kDa is expressed on almost all hematopoietic cells except for mature erythrocytes. CD45 has a functional role in hematopoietic cell activation and differentiation. Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. Therefore, a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin’s lymphoma, some T-cell lymphomas, and some leukemias), so its absence does not rule out a hematolymphoid tumor. CD-45 antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.
Intended Use: IVD