Anti-Claudin 5, Clone EP224

Catalog Number
AN718-10M
(100 tests - i6000)
Qty:
AN718-5M
(6 ml (RTU))
Qty:
AY718-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AY718-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FB-718N
(5 slides - Xmatrx)
Qty:
FG-718N
(5 slides - Manual)
Qty:
NU718-5UC
(0.5 ml (Conc.))
Qty:
NU718-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS
$0.00
0
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudin-5 is a member of the Claudin family. Mutations in Claudin-5 have been found in patients with velocardiofacial syndrome. Claudin-5 labels endothelial cells. It has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudin-5 expression has been found in lung adenocarcinoma and squamous carcinoma, in serous ovarian adenocarcinoma, increased found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma increased Claudin-5 expression is associated with aggressive behavior.
Intended Use: IVD