Anti- CNPase (Myelin), Clone SMI 91

Catalog Number
AM959-10M
(10 mL (RTU))
Qty:
AM959-5M
(6 ml (RTU))
Qty:
AX959-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX959-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
MU959-5UC
(0.5 ml (Conc.))
Qty:
MU959-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Brain stained with CNPase

$0.00
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The high CNPase expression is seen in myelin-producing cells, including oligodendrocytes and Schwann cells. CNPase participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; accounts for roughly 4% of the total myelin protein in the central nervous system (CNS). CNPase binds to tubulin heterodimers and plays a role in tubulin polymerization and oligodendrocyte process outgrowth. The enzyme isolated from the mammalian brain is primarily a mixed dimer of approximately 94 kDa. The dimer consists of a varied proportion of CNP1 (46 kDa) and CNP2 (48 kDa) subunits in various species. Since the enzyme is a myelin-associated enzyme, it is of considerable interest in the study of diseases and disorders in which myelin is affected; such as multiple sclerosis, subacute sclerosing panencephalitis, acquired immunodeficiency with CNS involvement, and peripheral neuropathies.
Intended Use: RUO