Anti-Cytokeratin 16, Clone KRT16/2043R

Catalog Number
AN933-10M - (10 mL (RTU))Add to cart
AN933-5M - (6 mL (RTU))Add to cart
AY933-50D - (50 tests - Xmatrx Elite)Add to cart
AY933-YCD - (200 tests - Xmatrx Elite)Add to cart
NU933-5UC - (0.5 mL (Conc.))Add to cart
NU933-UC - (0.5 mL (Conc.))Add to cart

Skin stained with Cytokeratin 16

Cytokeratin 16 protein is a member of the keratin (type I) family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Epidermis-specific type I keratin that plays a key role in skin; acts as a regulator of innate immunity in response to skin barrier breach; required for some inflammatory checkpoint for the skin barrier maintenance. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues; including esophagus; tongue and hair follicles. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck; as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.
Intended Use: IVD