Anti-Cytokeratin 7, Clone KRT7/760

Catalog Number
AM944-10M
(10 mL (RTU))
Qty:
AM944-5M
(6 ml (RTU))
Qty:
AX944-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX944-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
MU944-5UC
(0.5 ml (Conc.))
Qty:
MU944-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Endometrium stained with Cytokeratin-7

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Anti-Cytokeratin 7 (CK7) antibody recognizes an intermediate filament protein (IFP) of 55 kDa. This monoclonal antibody (mAb) is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin and belongs to type II cytokeratin. Type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels and is found in most glandular and transitional epithelia; but not in the stratified squamous epithelia. Cytokeratin 7 is expressed in the epithelial cells of the ovary, lung, and breast but not of the colon, prostate, or gastrointestinal tract. Anti-Cytokeratin 7 mAb is highly useful in distinguishing ovarian carcinomas (CK 7+) from colon carcinomas (CK 7-).
Intended Use: IVD