Anti-E Cadherin, Clone EP6

Catalog Number
AN725-10M - (100 tests - i6000)Add to cart
AN725-5M - (6 mL (RTU))Add to cart
AY725-50D - (50 tests - Xmatrx Elite)Add to cart
AY725-YCD - (200 tests - Xmatrx Elite)Add to cart
FB-725N - (5 slides - Xmatrx)Add to cart
FG-725N - (5 slides - Manual)Add to cart
NU725-5UC - (0.5 mL (Conc.))Add to cart
NU725-UC - (1 mL(Conc.))Add to cart
Datasheet
SDS

Breast carcinoma stained with anti-E-cadherin using DAB chromogen

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E-Cadherin is a 120-kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells. Its association with catenins is necessary for cell-cell adhesion. Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties. E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas. Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.
Intended Use: IVD