Anti-Ferritin Light chain, Clone FTL/1389

Catalog Number
AM935-10M
(10 mL (RTU))
Qty:
AM935-5M
(6 ml (RTU))
Qty:
AX935-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX935-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
MU935-5UC
(0.5 mL (conc))
Qty:
MU935-UC
(1 mL (conc))
Qty:
Datasheet
SDS

Kidney tissue stained with Ferritin light chain antibody

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Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains: ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage - the oxidation of Fe (II); whereas ferritin light chains promote the nucleation of ferrihydrite; enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms (hereditary hyperferritinemia cataract syndrome) in which light chain ferritin is overexpressed in serum and tissues.
Intended Use: RUO