Anti-N-Cadherin, Clone EPR1792Y

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N-Cadherin (Cadherin2) is a calcium-dependent transmembrane protein involved in cell-cell adhesion. N-cadherin functions during gastrulation to regulate mesenchymal morphogenesis and angiogenesis. N-Cadherin has been noted for its role in cancer progression, particularly tumor metastasis. In the progression of a tumor, metastasis is often facilitated by the upregulation of N-cadherin. The aberrant expression of N-cadherin allows transendothelial migration, which is needed, for metastasis to occur while the lack of N-cadherin will inhibit it.
Intended Use: IVD