Anti-Stat5-Alpha (C-term), Clone E289

Catalog Number
AN480-10M - (100 tests - i6000)Add to cart
AN480-5M - (6 mL (RTU))Add to cart
NU480-5UC - (0.5 mL (Conc.))Add to cart
NU480-UC - (1 mL(Conc.))Add to cart
Datasheet
SDS
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Stat5 is part of a 7 protein family known as signal transducer and activator of transcription (STAT) which contributes to signal transduction by cytokine, hormone and growth factor. Signal transducer and activator of transcription 5 (Stat5) functions both in signal translocated to the nucleus in response to phosphorylation. Stat-alpha tyrosine phosphorylation is activated predominantly by IL-2, but also by IL-3, IL-5, IL-7, IL-9, IL-15, G-CSF and GM-CSF. Tyrosine phosphorylation is required for maximal transcriptional activity. NCoA-1/SRC-1 acts as coactivator for both the alpha and beta isoforms of Stat5.
Intended Use: IVD