BCR/ABL Dual Color Dual Fusion Probe

Catalog Number
FP071-10X
(10 tests(RTU))
Qty:
FP071-20X
(20 tests(RTU))
Qty:
Datasheet
SDS

Tissue section with translocation affecting the BCR/ABL loci as indicated by one separate orange signal, one separate green signal and two orange/green fusion signals.

BCR/ABL Dual Color Dual Fusion Probe hybridized to normal interphase cells as indicated by two orange and two green signals in each nucleus.

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The specific translocations involving the chromosomal region 9q34 harboring the ABL (a.k.a ABL1) gene, and the chromosomal region 22q11, harboring the BCR (a.k.a. BCR1) gene has affinity to BioGenex eFISH BCR/ABL Dual Color Dual Fusion Probe. With the use of appropriate filter sets, the hybridization signals of the labeled BCR gene appear green; the hybridization signals of the labeled ABL gene appear orange. In interphases of normal cells or cells without a t(9;22)(q34;q11) translocation, two separate green and two separate orange signals appear. A t(9;22)(q34;q11) translocation is indicated by two green/orange fusion signals in addition to one separate green signal and one separate orange signal.
Intended Use: RUO