CCND1/CEN 11 Dual Color Probe

Catalog Number
(10 tests(RTU))
(20 tests(RTU))

Polysomy of chromosome 11 as indicated by three orange (CEN 11) and three green (CCND1) signals in each nucleus.

eFISH CCND1/CEN11 Dual Color Probe hybridized to normal interphase cells as indicated by two orange and two green signals in each nucleus.

eFISH CCND1/CEN 11 Dual Color Probe has affinity to CCND1 gene. The cyclin D1 gene (a.k.a. CCND1 or PRAD1) is located in the chromosomal region 11q13 and encodes a regulatory subunit of cyclin-dependent kinases that promote progression through the cell cycle. eFISH CCND1/CEN 11 dual Color Probe is a mixture of an orange fluorochrome direct labeled CEN 11 probe specific for the alpha satellite centromeric region of chromosome 11 (D11Z1) and a green fluorochrome direct labeled CCND1 probe specific for the CCND1 gene at 11q13.
Intended Use: RUO