COL1A1/PDGFB Dual Color Dual Fusion Probe

Catalog Number
FP052-10X
(10 tests(RTU))
Qty:
FP052-20X
(20 tests(RTU))
Qty:
Datasheet
SDS

Tissue section with translocation affecting the COL1A1/PDGFB loci as indicated by one separate orange signal, one separate green signal, and two orange/green fusion signals.

eFISH COL1A1/PDGFB Dual Color Dual Fusion Probe hybridized to normal interphase cells as indicated by two orange and two green signals in each nucleus.

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The specific translocations involving the chromosomal region 17q21 harboring the COL1A1 (a.k.a.OI4) gene, and the chromosomal region 22q13, harboring the PDGFB (a.k.a PDGF2,SIS) gene has affinity by BioGenex eFISH COL1A1/PDGFB Dual Color Dual Fusion Probe. The use of eFISH COL1A1/PDGFB Dual Color Dual Fusion Probe along with appropriate filters produces orange signal for hybridization regions of COL1A1 and green signal for labeled PDGFB gene. Normal interphase cells or cells without t(17;22)(q21;q13) translocation, two separate orange and two separate green signals are observed. Translocation of t (17; 22) (q21; q13) is indicated by the two orange/two green fusion signals.
Intended Use: RUO