EWSR1 Dual Color Break Apart Probe

Catalog Number
FP048-10X
(10 tests(RTU))
Qty:
FP048-20X
(20 tests(RTU))
Qty:
Datasheet
SDS

Tissue section with translocation affecting the 22q12 locus as indicated by one non-rearranged orange/green fusion signal, one orange signal, and one separate green signal indicating the translocation.

EWSR1 Dual Color Break Apart Probe hybridized to normal interphase cells as indicated by two orange/green fusion signals per nucleus

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Translocations involving the chromosomal region 22q12 harboring the EWSR1 (Ewing sarcoma breakpoint region 1) gene (a.k.a. EWS) is detected by Biogenex e FISH EWSR1 Dual Color Break Apart Probe. Translocations involving the chromosomal region 22q12 are found in 90-95% of patients with Ewing sarcoma or peripheral primitive neuroectodermal tumors (PNET). eFISH EWSR1 Dual Color Break Apart Probe is a mixture of two direct labeled probes hybridizing to the 22q12 band. The orange fluorochrome direct labeled probe hybridizes proximal and extends inward into intron 4 of the EWSR1 gene, the green fluorochrome direct labeled probe hybridizes distal to that gene.
Intended Use: RUO