FGFR1/CEN 8 Dual Color Probe

Catalog Number
(10 tests(RTU))
(20 tests(RTU))

Tissue section with interphase cells showing amplification of the FGFR1 gene (green) and partly polysomy 8 (orange).

eFISH FGFR1/CEN 8 Dual Color Pro hybridized to normal interphase cells as indicated by two orange and two green signals in each nucleus

FGFR1 gene amplification frequently observed in malignant tumors. eFISH FGFR1/CEN 8 Dual Color Probe has affinity to FGFR1gene. The FGFR1 (fibroblast growth factor receptor 1) gene is located in the chromosomal region 8p11.23-p11.22 and encodes a transmembrane receptor tyrosine kinase. The BioGenex eFISH FGFR1/CEN 8 Dual Color Probe is a mixture of an orange fluorochrome direct labeled CEN 8 probe specific for the alpha satellite centromeric region of chromosome 8 (D8Z2) and a green fluorochrome direct labeled FGFR1 probe specific for the FGFR1 gene at 8p11.23- p11.22.
Intended Use: RUO