MDM2/CEN 12 Dual Color Probe

Catalog Number
FP038-10X
(10 tests(RTU))
Qty:
FP038-20X
(20 tests(RTU))
Qty:
Datasheet
Datasheet (Automation only)
SDS

Tissue section with amplification of the MDM2 gene (green), CEN 12 (orange).

Normal interphase cells, MDM2 (green), CEN 12 (orange)

$0.00
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eFISH MDM2/CEN 12 Dual Color Probe has affinity to MDM2 gene. The MDM2 (mouse double minute 2) gene is located in the chromosomal region 12q15 and encodes for an E3 ubiquitin ligase which acts as a major negative regulator of the tumor suppressor p53. eFISH MDM2/CEN 12 Dual Color Probe is a mixture of an orange fluorochrome direct labeled CEN 12 probe specific for the alpha satellite centromeric region of chromosome 12 (D12Z3) and a green fluorochrome direct labeled SPEC MDM2 probe hybridizing distal and proximal to the human MDM2 gene in the chromosomal region 12q15.
Intended Use: RUO