PML/RARA Dual Color Dual Fusion Probe

Catalog Number
FP073-10X
(10 tests(RTU))
Qty:
FP073-20X
(20 tests(RTU))
Qty:
Datasheet
SDS

Tissue section with translocation affecting the PML/RARA loci as indicated by one separate orange signal, one separate green signal, and two orange/green fusion signals.

eFISH PML/RARA Dual Color Dual Fusion Probe hybridized to normal interphase cells as indicated by two orange and two green signals in each nucleus.

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The translocation t(15;17)(q24;q21) affecting the PML gene in the chromosomal region 15q24 and the RARA locus in 17q21 has affinity to eFISH PML/RARA Dual Color Dual Fusion Probe. Chromosome where there is no t(15;17)(q24;q21) translocation produces two green and two orange signals separately. Where as in regions of no t (15; 17) (q24; q21) translocation, the signals appear as two green/orange fusion signals in addition to a separate single green and orange signal.
Intended Use: RUO