TERT/5q31 Dual Color Probe

Catalog Number
(10 tests(RTU))
(20 tests(RTU))

SPEC TERT/5q31 Dual Color Probe hybridized to melanoma tissue section showing normal cell as indicated by two green and two orange signals in each nucleus and cells with TERT gene amplification as indicated by multiple green signals per nucleus.

eFISH TERT/5q31 Dual Color Probe has affinity to TERT gene. The TERT (telomerase reverse transcriptase) gene is located in the chromosomal region 5p15.33 and encodes the reverse transcriptase component of the human telomerase. eFISH TERT/5q31 Dual Color Probe is a mixture of a green fluorochrome direct labeled TERT probe hybridizing to the TERT gene in the chromosomal region 5p15.33 and an orange fluorochrome direct labeled 5q31 probe specific for the chromosomal region 5q31 harboring the EGR1 gene. Since chromosomes 1, 5, and 19 share the same repetitive sequences, probes specific for 5q31 are commonly used for chromosome 5 copy number detection.
Intended Use: RUO