Anti-Anaplastic Lymphoma Kinase (ALK)

Catalog Number
AN874-10M
(100 tests - i6000)
Qty:
AN874-5M
(6 ml (RTU))
Qty:
AY874-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AY874-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FB-874N
(5 slides - Xmatrx)
Qty:
FG-874N
(5 slides - Manual)
Qty:
NU874-5UC
(0.5 ml (Conc.))
Qty:
NU874-UC
(1 ml (Conc.))
Qty:
Datasheet

Anaplastic lymphoma stained with anti-Human ALKusing DAB chromogen

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Anaplastic lymphoma kinase is a receptor tyrosine kinase. Chromosomal translocations involving ALK have been found to be associated with different diseases such as anaplastic large cell lymphomas (ALCLs) and non small-cell lung cancer (NSCLC). The constitutively active fusion proteins are responsible for most of anaplastic large cell nonHodgkin’s lymphomas. The EML4-ALK fusion gene is responsible for approximately 3-5% of NSCLC. EML4-ALK-rearrangement in NSCLC is exclusive and not found in EGFR- or KRAS-mutated tumors.
Intended Use: IVD