Anti-Calponin-1, Clone EP798Y

Catalog Number
AX502-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX502-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FG-502N
(5 slides - Manual)
Qty:
NU502-5UC
(0.5 ml (Conc.))
Qty:
NU502-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS
$0.00
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Calponin is a smooth muscle specific, actin-, tropomysin- and calmodulin- binding protein thought to be involved in regulation of actomyosin as well as the regulation or modulation of contraction. Calponin binds filamentous actin (F-actin) through two distinct sites ABS1 and ABS2, with an affinity in the low micromolar range. Immuno reactivity for Calponin, along with alpha-smooth muscle actin and smooth muscle myosin heavy chains, confirms the known neoplastic myoepithelial component of adenoid cystic carcinomas and epithelial-myoepithelial carcinomas. The consistently positive staining pattern in adenoid cystic carcinomas my be diagnostically useful in discriminating histological similar but consistently negative polymorphous low-grade adenocarcinomas.
Intended Use: IVD