Anti-CD146, Clone EP54

Catalog Number
AN716-10M
(100 tests - i6000)
Qty:
AN716-5M
(6 ml (RTU))
Qty:
AY716-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AY716-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FB-716N
(5 slides - Xmatrx)
Qty:
FG-716N
(5 slides - Manual)
Qty:
NU716-5UC
(0.5 ml (Conc.))
Qty:
NU716-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS
$0.00
0
CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene. CD146 labels endothelial cells, smooth muscle cells, intermediate trophoblast, subpopulation of T cells and peripheral neuronal cells. In tumor, CD146 is expressed on tumor cells derived from peripheral nervous system, melanoma and clear cell sarcoma. CD146 has been used a marker for intermediate trophoblast. It has been reported that CD146 is useful in differentiation of mesothelioma (CD146 positive) and reactive mesothelium (CD146 negative) CD146 is associated with tumor progression and the development of metastasis in human malignant melanoma.
Intended Use: IVD