Anti-Cytokeratin 17, Clone E27

Catalog Number
AM572-10M
(100 tests - i6000)
Qty:
AM572-5M
(6 ml (RTU))
Qty:
AX572-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AX572-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FG-572M
(5 slides - Manual)
Qty:
MU572-5UC
(0.5 ml (Conc.))
Qty:
MU572-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Squamous Cell carcinoma stained with Anti-CK17 using DAB chromogen

$0.00
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CK17 is the type I intermediate filament chain keratin. It is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells. Cytokeratin 17 is 46 kD intermediate filament found in simple epithelia sometimes in association with Cytokeratin 7. This antibody has been used to distinguish cervical immature squamous metaplasia from high grade cervical intraepithelial neoplasia (CIN III). Anti-CK 17 also labels myoepithelial cells in the benign breast tissue. CK 17 labelling of breast carcinoma cells (so-called basal phenotype) has been associated with a poor prognosis.
Intended Use: IVD