Anti-Oct-2

Catalog Number
AN830-10M
(100 tests - i6000)
Qty:
AN830-5M
(6 ml (RTU))
Qty:
AY830-50D
(50 tests - Xmatrx Elite/Ultra)
Qty:
AY830-YCD
(200 tests - Xmatrx Elite/Ultra)
Qty:
FB-830N
(5 slides - Xmatrx)
Qty:
FG-830N
(5 slides - Manual)
Qty:
NU830-5UC
(0.5 ml (Conc.))
Qty:
NU830-UC
(1 ml (Conc.))
Qty:
Datasheet
SDS

Tonsil tissue stained with anti-Human OCT-2 using DAB chromogen

$0.00
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Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5- ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin’s lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs.
Intended Use: IVD