Hsa-miR-153

Catalog Number
FB-HM153
(5 control slides)
Qty:
HM153-100
(Probes, 25 tests - manual)
Qty:
Datasheet
SDS

Hsa-miR-153 detected in FFPE tissue stained with DAB

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miR-153 upregulation promoted tumor invasiveness by indirectly initiating matrix metalloprotease enzyme 9 productions. Overexpression of miR-153 in tumor cells enhanced the G1/S transitional promoter, cyclin D1 expression, and decreased cyclin-dependent kinase (CDK) inhibitor, p21(Cip1) expression via downregulation of PTEN tumor suppressor gene and activated AKT signaling. The fluorescinated hsa-miR-153 probe is designed to localize this miRNA in FFPE tissue by in situ hybridization.
Intended Use: ASR