Hsa-miR-627

Catalog Number
FB-HM627
(5 control slides)
Qty:
HM627-100
(Probes, 25 tests - manual)
Qty:
Datasheet
SDS

Hsa-miR-627 detected in FFPE tissue stained with DAB

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miR-627 is a major epigenetic regulator in vitamin D induced growth inhibition of tumorous cells upon stimulation by calcitriol. miR-627 acts on target gene JMJD1A (jumonji domain containing 1A), the gene encoding a histone demethylase which is upregulated under hypoxia and promotes tumor growth in tumor cells. Overexpression of miR-627 decreased JMJD1A and suppressed the expression of growth-promoting and differentiating genes, GDF15. The fluorescinated hsa-miR-627 probe is designed to localize this miRNA in FFPE tissue by in situ hybridization.
Intended Use: ASR